Signaling pathway

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Akt3 Polyclonal Antibody

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Article Number: PG3211
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560

Detailed Information

Recommended dilution ratio : WB 1:1000-2000
Compose : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Polyclonal

Antigen & Target Information

Specificity : The antibody detects endogenous Akt3 protein.
Gene name : AKT3
Protein Name : RAC-gamma serine/threonine-protein kinase
Alias : AKT3;PKBG;RAC-gamma serine/threonine-protein kinase;Protein kinase Akt-3;Protein kinase B gamma;PKB gamma;RAC-PK-gamma;STK-2

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus . Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.

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