Signaling pathway

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CD2 (PN0099) Nb-FC recombinant antibody

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Article Number: PA0214
Delivery time: 现货
Price: 100ug/2200

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0391

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD141 protein.
Gene name : THBD THRM
Protein Name : T-cell surface antigen CD2 (Erythrocyte receptor) (LFA-2) (LFA-3 receptor) (Rosette receptor) (T-cell surface antigen T11/Leu-5) (CD antigen CD2)
Alias : CD2; SRBC; T-cell surface antigen CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD2

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded byThis intronless gene is an endothelial-specific type I membrane receptor that binds thrombin.This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations inThis gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]

Cell localization : Membrane; Single-pass type I membrane protein.

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