Signaling pathway

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NF-κB p65 (PTR2315) mouse mAb

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Article Number: PH0842
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein G
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PTR2315

Antigen & Target Information

Specificity : This antibody detects endogenous levels of NF-κB p65 protein.
Gene name : RELATION
Protein Name : Transcription factor p65
Alias : RELA;NFKB3;Transcription factor p65;Nuclear factor NF-kappa-B p65 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Database connection:

Organism

Gene ID

SwissProt

Background:

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

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