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Signaling pathway
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Neurodegeneration—A Common Pathway Across Multiple Diseases (0)
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The AGE–RAGE signaling pathway in diabetic complications (0)
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PD-L1 Expression and the PD-1 Checkpoint Pathway in Cancer (0)
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Epithelial Cell Signaling in Helicobacter pylori Infection (0)
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Glioma-associated Kaposi’s sarcoma-associated herpesvirus infection (0)
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PL1504
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： NQO1
Application： WB, IHC, IF, IP, ELISA
Reactivity ： Human,Mouse,Rat,
MW(CalcμLated) ： 31 kDa
MW(Observed) ： 31 kDa
Host Species： Rabbit
Isotype ： IgG, Kappa
Conjugate ： Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200,
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： Protein A
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： PT0071R
Antigen & Target Information
Specificity ： Endogenous
Gene name ： >>Ubiquinone and other terpenoid-quinone biosynthesis;>>Metabolic pathways;>>Biosynthesis of cofactors;>>Pathways in cancer;>>Chemical carcinogenesis - reactive oxygen species;>>Hepatocellular carcinoma;>>Fluid shear stress and atherosclerosis
Protein Name ： NQO1
Alias ： NQO1;DIA4;NMOR1;NADH dehydrogenase [quinone] 1;Azoreductase;DT-diaphorase;DTD;Menadione reductase;NADH:quinone oxidoreductase 1;Phylloquinone reductase;Quinone reductase 1;QR1
Background：
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Cell localization ： Cytoplasm
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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