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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PL1300
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： TGFB1\TGFB3
Application： WB, IHC, IF, ELISA
Reactivity ： Human,Mouse,Rat,
MW(CalcμLated) ： 44 kD
MW(Observed) ： 44 kD, 13 kD
Host Species： Rabbit
Isotype ： IgG, Kappa
Conjugate ： Unmodified
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:1000-1:4000; WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： Protein A
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： PT0402R
Antigen & Target Information
Specificity ： Endogenous
Gene name ： TGFB1 TGFB3
Protein Name ： Transforming growth factor beta-1 proprotein; Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1); Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 (TGF-beta-3);
Alias ： Transforming growth factor beta-1 proprotein; Latency-associated peptide; LAP; Transforming growth factor beta-1; TGF-beta-1; Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3; TGF-beta-3;
Database connection:
Organism
Gene ID
SwissProt
Background：
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic
Cell localization ： Secreted
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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