Signaling pathway

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Nucleophosmin (ABT210) IHC kit

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Article Number: PP0139
Delivery time: 一周
Price: 1900/10 mL 15000/100 mL
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Category:


Target: Nucleophosmin
Application: IHC
Reactivity : Human
Host Species: Mouse
Isotype : IgG2b, Kappa

隐藏域元素占位

Detailed Information

Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : 2°C to 8°C/1 year
Clonality : Monoclonal

Antigen & Target Information

Specificity : The antibody can specifically recognize human Nucleophosmin protein.
Gene name : NPM1 NPM
Protein Name : Nucleophosmin
Alias : NPM1;NPM;Nucleophosmin;NPM;Nucleolar phosphoprotein B23;Nucleolar protein NO38;Numatrin

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009],

Cell localization : Nuclear, Cytoplasmic

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