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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH0189
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： p53
Application： IHC, ELISA
Reactivity ： Human,
MW(CalcμLated) ： 53 kD
MW(Observed) ： 53 kD
Host Species： Mouse
Isotype ： IgG2a, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:50-100; ELISA 1:500-5000
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： ABT-P53
Antigen & Target Information
Specificity ： The antibody can recognize human wild type and mutant P53 protein.
Gene name ： TP53 P53
Protein Name ： Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;p53;p53 tumor suppressor;P53_HUMAN;Phosphoprotein p53;Tp53;Transformation related protein 53;TRP53;tumor antigen p55;Tumor protein 53;Tumor protein p53;Tumor suppressor p53
Alias ： Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;p53;p53 tumor suppressor;P53_HUMAN;Phosphoprotein p53;Tp53;Transformation related protein 53;TRP53;tumor antigen p55;Tumor protein 53;Tumor protein p53;Tumor suppressor p53;
Background：
tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Cell localization ： Nuclear
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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