Signaling pathway

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CD141 (ABT145) mouse mAb

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Article Number: PH0176
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: CD141
Application: IHC, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 62 kD
MW(Observed) : 100 kD
Host Species: Mouse
Isotype : IgG2b, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:50-200; ELISA 1:500-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : ABT145

Antigen & Target Information

Specificity : The antibody can specifically recognize human CD141 protein.
Gene name : THBD THRM
Protein Name : CD141
Alias : Thrombomodulin; TM; Fetomodulin; CD antigen CD141;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],

Cell localization : Membranous

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