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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH0124
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target： Glypican-3
Application： IHC, ELISA
Reactivity ： Human,
MW(CalcμLated) ： 66 kDa
MW(Observed) ： 58 kD
Host Species： Mouse
Isotype ： IgG1, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:50-200; ELISA 1:500-5000
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： ABT180
Antigen & Target Information
Specificity ： The antibody can specifically recognize human Glypican-3 protein.
Gene name ： GPC3 OCI5
Protein Name ： Glypican-3 (GPC3)
Alias ： Glypican-3;GTR2-2;Intestinal protein OCI-5;MXR7;[Cleaved into: Secreted glypican-3]
Background：
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],
Cell localization ： Cytoplasmic
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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