Signaling pathway

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CD44 (ABT147) mouse mAb

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Article Number: PH0172
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: CD44
Application: IHC, ELISA
Reactivity : Human,
MW(CalcμLated) : 81kD
MW(Observed) : 81kD
Host Species: Mouse
Isotype : IgG2b, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-400; ELISA 1:500-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : ABT147

Antigen & Target Information

Specificity : The antibody can specifically recognize human CD44 protein.
Gene name : CD44 LHR MDU2 MDU3 MIC4
Protein Name : CD44
Alias : CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD antigen CD44;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008],

Cell localization : Membranous

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