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TEL: 15392937510
Article Number: PH0277
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target: Actin_Muscle Specific
Application: IHC, ELISA
Reactivity : Human,Mouse,Rat,Monkey,Bovin,Pig,Chick,
MW(Observed) : 42 kDa
Host Species: Mouse
Isotype : IgG1, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:200-400; ELISA 1:500-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : ABT-MSA
Antigen & Target Information
Specificity : The antibody can specifically recognize proteins from smooth muscle, myocardium and skeletal muscle α actin and smooth muscle derived γ actin, and β actin or non smooth muscle derived γ actin does not respond.
Gene name : Actin, Muscle Specific
Protein Name : α-Skeletal Muscle Actin (α-SA); α-Cardiac Muscle Actin (α-CA); α-Smooth Muscle Actin (α-SMA); γ-Smooth Muscle Actin (γ-SMA);
Database connection:
Background:
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008],


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