Signaling pathway

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DERL2 Polyclonal Antibody

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Article Number: PG5748
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: DERL2
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 26 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : DERL2 Polyclonal Antibody detects endogenous levels of protein.
Gene name : DERL2 DER2 FLANA CGI-101 SBBI53
Protein Name : Derlin-2 (Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

derlin 2(DERL2) Homo sapiens Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM, Mar 2008],

Cell localization : Endoplasmic reticulum membrane ; Multi-pass membrane protein .

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