Signaling pathway

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CD142 (PN0243) Nb-FC recombinant antibody

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Article Number: PA0300
Delivery time: 现货
Price: 100ug/2200
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Target: CD48
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0197

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD48 protein.
Gene name : CD48 BCM1 BLAST1
Protein Name : Tissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142)
Alias : Coagulation Factor III; Tissue Factor; TF; Thromboplastin; platelet tissue factor; factor III; factor 3; F3; F-3; TFA

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Dec 2011]

Cell localization : Cell membrane ; Lipid-anchor, GPI-anchor . Secreted .

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