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Article Number: PL0265
Delivery time: 现货
Price: 100 μL/1800
Category:
Target: RORγ
Application: WB, IHC, IF, IP, ELISA
Reactivity : Mouse
MW(CalcμLated) : 58 kD
MW(Observed) : 58 kD
Host Species: Rabbit
Isotype : IgG, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clone Number : Monoclonal
Antigen & Target Information
Specificity : Endogenous
Gene name : RORC
Protein Name : Nuclear receptor ROR-gamma
Alias : RORC;NR1F3;RORG;RZRG;Nuclear receptor ROR-gamma;Nuclear receptor RZR-gamma;Nuclear receptor subfamily 1 group F member 3;Retinoid-related orphan receptor-gamma
Background:
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],


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