Signaling pathway

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EphB4 Monoclonal Antibody

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Article Number: PH1699
Delivery time: 一周
Price: 100 μL/2200
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Target: EphB4
Application: WB, IHC, IF, ELISA
Reactivity : Human
MW(CalcμLated) : 108 kD
Host Species: Mouse

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Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : EphB4 Monoclonal Antibody detects endogenous levels of EphB4 protein.
Gene name : EPHB4
Protein Name : Ephrin type-B receptor 4
Alias : EPHB4;HTK;MYK1;TYRO11;Ephrin type-B receptor 4;Hepatoma transmembrane kinase;Tyrosine-protein kinase TYRO11

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane ; Single-pass type I membrane protein .

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