Signaling pathway

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PP2A α and β mouse mAb

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Article Number: PH1272
Delivery time: 一周
Price: 100 μL/2200
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Target: PP2A α and β
Application: WB,IP
Reactivity : Human,Mouse,Rat
MW(Observed) : 36 kD
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of PP2A alpha and PP2A beta.
Gene name : ppp2cb
Alias : PP2A beta;PP2A-beta;PP2AB_HUMAN;PP2Abeta;PP2CB;Ppp2cb;Protein phosphatase 2;formerly 2A;, catalytic subunit, beta isoform;Protein phosphatase 2 catalytic subunit beta isozyme;Protein phosphatase 2, catalytic subunit, beta isoform;Protein phosphatase 2A catalytic subunit beta isoform;Protein phosphatase type 2A catalytic subunit;Serine/threonine protein phosphatase 2A catalytic subunit beta;Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform.

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010],

Cell localization : Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.

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