Signaling pathway

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ACACB rabbit pAb

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Article Number: PD0695
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ACACB
Application: World Bank
Reactivity : Human,Mouse
MW(CalcμLated) : 270 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of ACACB at Human
Gene name : ACACB ACC2 ACCB
Protein Name : ACACB
Alias : ACACB,Acetyl CoA carboxylase 2,ACC beta,ACC2,ACCB,AcetylCoA carboxylase 2,ACCbeta,ACCβ,ACC β,

Database connection:

Organism

Gene ID

SwissProt

Background:

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008],

Cell localization : Mitochondrion .

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