Signaling pathway

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AP2B1 rabbit pAb

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Article Number: PD1539
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: AP2B1
Application: World Bank
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 103 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of AP2B1 at Human/Mouse/Rat
Gene name : AP2B1 ADTB2 CLAPB1
Protein Name : AP2B1

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Cell membrane . Membrane, coated pit ; Peripheral membrane protein ; Cytoplasmic side . AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.

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