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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PA0529
Delivery time: 现货
Price: 100ug/2200
Target： CD13
Application： ELISA
Reactivity ： Human
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose ： Phosphate-buffered solution
Source ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process ： Recombinant Expression and Affinity purified
Storage ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration ： Please check the information on the tube
Clonality ： Monoclonal
Clone Number ： PN0020
Antigen & Target Information
Specificity ： This recombinant monoclonal antibody can detects endogenous levels of CD13 protein.
Gene name ： ANPEP APN CD13 PEPN
Protein Name ： Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
Alias ： TIM3;CD366;KIM-3;SPTCL;TIMD3;Tim-3;TIMD-3;HAVcr-2;CD366 nanobody;TIM-3 nanobody;
Background：
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes ofThis class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is
Cell localization ： Cell membrane ; Single-pass type II membrane protein . Also found as a soluble form. .
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Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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