Signaling pathway

Contact Us

15392937510

Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510

Image Name

AT2B2 Polyclonal Antibody

Copy

Download
Article Number: PG7650
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
+


Target: AT2B2
Application: WB, ELISA
Reactivity : Human, Rat
MW(Observed) : 136 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : AT2B2 Polyclonal Antibody detects endogenous levels of protein.
Gene name : ATP2B2 PMCA2
Protein Name : Plasma membrane calcium-transporting ATPase 2 (PMCA2) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced tran

Cell localization : Cell membrane; Multi-pass membrane protein. Cell junction, synapse. [Isoform WA]: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. [Isoform WB]: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. [Isoform XB]: Basolateral cell membrane; Multi-pass membrane protein. [Isoform ZA]: Basolateral cell membrane; Multi-pass membrane protein. [Isoform ZB]: Basolateral cell membrane; Multi-pass membrane protein.

Recommended

Relevant Literature

Leave a message for inquiry

Please leave your inquiry, and we will contact you as soon as possible.

Submit