Signaling pathway

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CK18 Polyclonal Antibody

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Article Number: PG3250
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Cytokeratin 18
Application: World Bank
Reactivity : Human
MW(Observed) : 46 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:1000-2000
Compose : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Polyclonal

Antigen & Target Information

Specificity : The antibody detects endogenous Cytokeratin 18 protein.
Gene name : KRT18
Protein Name : Keratin type I cytoskeletal 18
Alias : KRT18;CYK18;PIG46;Keratin, type I cytoskeletal 18;Cell proliferation-inducing gene 46 protein;Cytokeratin-18;CK-18;Keratin-18;K18

Database connection:

Organism

Gene ID

SwissProt

Background:

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm, perinuclear region. Nucleus, nucleolus.

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