Signaling pathway

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OCLN (PTR1394) mouse mAb

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Article Number: PH0617
Delivery time: 一个月
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: OCLN
Application: WB, IF, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 59 kDa
MW(Observed) : 59 kDa
Host Species: Mouse
Isotype : IgG1, kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PTR1394

Antigen & Target Information

Specificity : This antibody detects endogenous levels of OCLN protein.
Gene name : OCLN
Protein Name : Occludin;OCN

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],

Cell localization : Membrane

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