Signaling pathway

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THBG Polyclonal Antibody

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Article Number: PG7309
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: THBG
Application: WB, ELISA
Reactivity : Human, Rat, Mouse
MW(Observed) : 45 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : THBG Polyclonal Antibody detects endogenous levels of protein.
Gene name : SERPINA7 TBG
Protein Name : Thyroxine-binding globulin (Serpin A7) (T4-binding globulin)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.[provided by RefSeq, Jun 2012],

Cell localization : Secreted.

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