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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH0534
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： Vitamin D Receptor
Application： WB, IF, ELISA
Reactivity ： Human,
MW(CalcμLated) ： 48 kD
MW(Observed) ： 37 kD
Host Species： Mouse
Isotype ： IgG1, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： Protein G
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： PTR2542
Antigen & Target Information
Specificity ： This antibody detects endogenous levels of Vitamin D Receptor protein.
Gene name ： VDR NR1I1
Protein Name ： Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1)
Alias ： VDR;NR1I1;Vitamin D3 receptor;VDR;1;25-dihydroxyvitamin D3 receptor;Nuclear receptor subfamily 1 group I member 1
Database connection:
Background：
vitamin D (1,25- dihydroxyvitamin D3) receptor(VDR) Homo sapiens This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011],
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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