Signaling pathway

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IRF-1 Polyclonal Antibody

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Article Number: PD2390
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: IRF-1
Application: WB, ELISA, IHC
Reactivity : Human,Mouse,Rat
MW(Observed) : 36 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : IRF-1 Polyclonal Antibody detects endogenous levels of IRF-1 protein.
Gene name : IRF1
Protein Name : Interferon regulatory factor 1
Alias : IRF1; Interferon regulatory factor 1; IRF-1

Database connection:

Organism

Gene ID

SwissProt

Background:

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus . Cytoplasm . MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. .

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