Signaling pathway

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MEFV rabbit pAb

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Article Number: PG3389
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MEFV
Application: World Bank
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 86 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:1000-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of human MEFV
Gene name : MEFV MEF
Protein Name : Pyrin (Marenostrin)

Database connection:

Organism

Gene ID

SwissProt

Cell localization : [Isoform 1]: Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection, lamellipodium. Nucleus. Cytoplasm. Cytoplasmic vesicle, autophagosome. Associated with microtubules and with the filamentous actin of perinuclear filaments and peripheral lamellar ruffles (PubMed:11468188). In pre-apoptotic cells, colocalizes with PYCARD/ASC in large specks (inflammasomes) (PubMed:11468188). In migrating monocytes, strongly polarized at the leading edge of the cell where it colocalizes with polymerizing actin and PYCARD/ASC (PubMed:11468188). .; [Isoform 2]: Nucleus .

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