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Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH1500
Delivery time: 一周
Price: 100 μL/2200
Category:
Target: PDK1
Application: WB, IHC, IF, Flow Cyt, ELISA
Reactivity : Human, Rat, Monkey
MW(CalcμLated) : 49 kD
Host Species: Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Antigen & Target Information
Specificity : PDK1 Monoclonal Antibody detects endogenous levels of PDK1 protein.
Gene name : PDK1
Protein Name : [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 mitochondrial
Alias : PDK1;PDHK1;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;mitochondrial;Pyruvate dehydrogenase kinase isoform 1
Background:
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],


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