Signaling pathway

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PDK1 Monoclonal Antibody

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Article Number: PH1500
Delivery time: 一周
Price: 100 μL/2200
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Target: PDK1
Application: WB, IHC, IF, Flow Cyt, ELISA
Reactivity : Human, Rat, Monkey
MW(CalcμLated) : 49 kD
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : PDK1 Monoclonal Antibody detects endogenous levels of PDK1 protein.
Gene name : PDK1
Protein Name : [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 mitochondrial
Alias : PDK1;PDHK1;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;mitochondrial;Pyruvate dehydrogenase kinase isoform 1

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],

Cell localization : Mitochondrion matrix .

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