Signaling pathway

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DSC2 Polyclonal Antibody

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Article Number: PG6383
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: DSC2
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 99kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : DSC2 Polyclonal Antibody detects endogenous levels of protein.
Gene name : DSC2 CDHF2 DSC3
Protein Name : Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],

Cell localization : Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.

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