Signaling pathway

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Tubulin α-3C/D/E Polyclonal Antibody

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Article Number: PD3143
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Tubulin α-3C/D/E
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 50 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Tubulin α-3C/D/E Polyclonal Antibody detects endogenous levels of Tubulin α-3C/D/E protein.
Gene name : TUBA3C/D/TUBA3E
Protein Name : Tubulin alpha-3C/D chain/Tubulin alpha-3E chain
Alias : TUBA3C;TUBA2;TUBA3D;Tubulin alpha-3C/D chain;Alpha-tubulin 2;Alpha-tubulin 3C/D;Tubulin alpha-2 chain;TUBA3E;Tubulin alpha-3E chain;Alpha-tubulin 3E

Database connection:

Organism

Gene ID

SwissProt

Background:

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provid

Cell localization : nucleus, cytoplasm, microtubule,

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