Signaling pathway

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ETS1 Monoclonal Antibody

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Article Number: PH1688
Delivery time: 一周
Price: 100 μL/2200
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Target: ETS1
Application: WB, IHC, IF, Flow Cyt, ELISA
Reactivity : Human
MW(CalcμLated) : 50 kD
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : ETS1 Monoclonal Antibody detects endogenous levels of ETS1 protein.
Gene name : ETS1
Protein Name : Protein C-ets-1
Alias : Ets-1;ETS1;EWSR2;Protein C-ets-1;p54

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],

Cell localization : Cytoplasm . Nucleus . Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27. .

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