Signaling pathway

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COX IV Monoclonal Antibody (6C8), Cy5 Conjugated

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Article Number: PH1097
Delivery time: 两周
Price: 100 μL/2200

Detailed Information

Recommended dilution ratio : Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:IHC 1:50-300;IF 1:200 .
Compose : Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
Purification process : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage : Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
Concentration : 1 mg/mL
Clonality : Monoclonal
Clone Number : 6C8

Antigen & Target Information

Specificity : COX IV Monoclonal Antibody(6C8) Cy5 Conjugated specially designed for your Immunofluorescence analysis.
Gene name : COX4I1
Protein Name : Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Alias : COX4I1

Database connection:

Organism

Gene ID

SwissProt

Background:

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes

Cell localization : Mitochondrion inner membrane ; Single-pass membrane protein .

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