Signaling pathway

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CD300e (PN0402) Nb-FC recombinant antibody

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Article Number: PA0579
Delivery time: 现货
Price: 100ug/2200
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Target: CD141
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0395

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD141 protein.
Gene name : THBD THRM
Protein Name : CMRF35-like molecule 2 (CLM-2) (CD300 antigen-like family member E) (CMRF35-A5) (Immune receptor expressed on myeloid cells 2) (IREM-2) (Polymeric immunoglobulin receptor 2) (PIgR-2) (PIgR2) (Poly-Ig receptor 2) (CD antigen CD300e)
Alias : CMRF35-like molecule 2;CLM-2;CD300 antigen-like family member E;CMRF35-A5;Immune receptor expressed on myeloid cells 2;IREM-2;Polymeric immunoglobulin receptor 2;PIgR-2;PIgR2;Poly-Ig receptor 2;CD antigen CD300e;,CD300e nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded byThis intronless gene is an endothelial-specific type I membrane receptor that binds thrombin.This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations inThis gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]

Cell localization : Membrane; Single-pass type I membrane protein.

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