Signaling pathway

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HBB Polyclonal Antibody

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Article Number: PG6280
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: HBB
Application: WB, ELISA
Reactivity : Human, Rat
MW(Observed) : 16 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : HBB Polyclonal Antibody detects endogenous levels of protein.
Gene name : HBB
Protein Name : Hemoglobin subunit beta (Beta-globin) (Hemoglobin beta chain) [Cleaved into: LVV-hemorphin-7]

Database connection:

Organism

Gene ID

SwissProt

Background:

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008],

Cell localization : extracellular region, cytosol, hemoglobin complex, integral component of membrane, haptoglobin-hemoglobin complex, extracellular exosome, endocytic vesicle lumen, blood microparticle,

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