Signaling pathway

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Jak1 mouse mAb

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Article Number: PH1231
Delivery time: 一周
Price: 100 μL/2200

Detailed Information

Recommended dilution ratio : WB 1:200-1000; ICC 1:200; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of Jak1 and does not cross-react with related proteins.
Gene name : jak1
Alias : JAK 1;JAK 1A;JAK 1B;JAK-1;JAK1;JAK1_HUMAN;JAK1A;JAK1B;Janus kinase 1;a protein tyrosine kinase;Janus kinase 1;JTK3;Tyrosine protein kinase JAK 1;Tyrosine protein kinase JAK1;Tyrosine-protein kinase JAK1.

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Cell localization : Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.

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