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Article Number: PS0131
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: DNA polymerase β
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 38 kDa
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Modify-Modification : Acetyl
Recommended dilution ratio : WB 1:1000-2000; ELISA 1:5000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : This antibody detects endogenous levels of Human,Mouse,Rat DNA pol β (Acetyl Lys72)
Gene name : POLB
Protein Name : DNA pol β (Acetyl Lys72)
Alias : DNA polymerase beta; EC 4.2.99.-;
Database connection:
Background:
catalytic activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)., cofactor: Binds 2 magnesium ions per subunit., domain: Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity., function: Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity., PTM: Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity., similarity: Belongs to the DNA polymerase type-X family., subunit: Monomer.,


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