Signaling pathway

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MMP-9 Monoclonal Antibody

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Article Number: PH1546
Delivery time: 一周
Price: 100 μL/2200
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Target: MMP-9
Application: WB, IHC, IF, Flow Cyt, ELISA
Reactivity : Human
MW(CalcμLated) : 78 kD
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : MMP-9 Monoclonal Antibody detects endogenous levels of MMP-9 protein.
Gene name : MMP9
Protein Name : Matrix metalloproteinase-9
Alias : MMP9;CLG4B;Matrix metalloproteinase-9;MMP-9;92 kDa gelatinase;92 kDa type IV collagenase;Gelatinase B;GELB

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

matrix metallopeptidase 9(MMP9) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008],

Cell localization : Secreted, extracellular space, extracellular matrix .

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