Signaling pathway

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ACTN4 rabbit pAb

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Article Number: PG3071
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ACTN4
Application: World Bank
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 100 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of ACTN4 in Human, Mouse, and Rat.
Gene name : ACTN4
Protein Name : Alpha-actinin-4 (F-actin cross-linking protein) (Non-muscle alpha-actinin 4)

Database connection:

Organism

Gene ID

SwissProt

Cell localization : Nucleus . Cytoplasm . Cell junction . Cytoplasm, cytoskeleton, stress fiber . Cytoplasm, perinuclear region . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity). Nuclear translocation can be induced by the PI3 kinase inhibitor wortmannin or by cytochalasin D. Exclusively localized in the nucleus in a limited number of cell lines (breast cancer cell line MCF-7, oral floor cancer IMC-2, and bladder cancer KU-7). .

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