Signaling pathway

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LAMP1 (PN0106) Nb-FC recombinant antibody

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Article Number: PA0314
Delivery time: 现货
Price: 100ug/2200
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Target: CD62L
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0039

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD62L protein.
Gene name : SELL LNHR LYAM1
Protein Name : Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)
Alias : LAMP1; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a

Database connection:

Organism

Gene ID

SwissProt

Background:

CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Cell localization : Cell membrane ; Single-pass type I membrane protein .

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