Signaling pathway

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K2C6B rabbit pAb

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Article Number: PG5610
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: K2C6B
Application: World Bank
Reactivity : Human,Mouse
MW(Observed) : 60 kDa
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of K2C6B at Human/Mouse
Gene name : KRT6B K6B KRTL1
Protein Name : K2C6B
Alias : Keratin, type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; K6B; Type-II keratin Kb10;

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],

Cell localization : keratin filament, extracellular exosome,

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