Signaling pathway

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Calcyclin Monoclonal Antibody

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Article Number: PH1800
Delivery time: 一周
Price: 100 μL/2200
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Target: Calcyclin
Application: WB, IHC, IF, ELISA
Reactivity : Human
MW(CalcμLated) : 26 kD
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : Calcyclin Monoclonal Antibody detects endogenous levels of Calcyclin protein.
Gene name : CACYBP
Protein Name : Calcyclin-binding protein
Alias : CACYBP;S100A6BP;SIP;PNAS-107;Calcyclin-binding protein;CacyBP;hCacyBP;S100A6-binding protein;Siah-interacting protein

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus . Cytoplasm . Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated.

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