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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH1432
Delivery time: 一周
Price: 100 μL/2200
Category:
Target： TBL1X
Application： WB, ELISA
Reactivity ： Human,Monkey
MW(CalcμLated) ： 62 kD
Host Species： Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process ： Affinity purification
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Antigen & Target Information
Specificity ： TBL1X Monoclonal Antibody detects endogenous levels of TBL1X protein.
Gene name ： TBL1X
Protein Name ： F-box-like/WD repeat-containing protein TBL1X
Alias ： TBL1X;TBL1;F-box-like/WD repeat-containing protein TBL1X;SMAP55;Transducin beta-like protein 1X;Transducin-beta-like protein 1;X-linked
Background：
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have bee
Cell localization ： Nucleus. Colocalized with MECP2 to the heterochromatin foci. .
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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