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Article Number: PH1510
Delivery time: 一周
Price: 100 μL/2200
Category:
Target: PAK2
Application: WB, IHC, IF, ELISA
Reactivity : Human,Monkey
MW(CalcμLated) : 58 kD
Host Species: Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Antigen & Target Information
Specificity : PAKγ Monoclonal Antibody detects endogenous levels of PAKγ protein.
Gene name : PAK2
Protein Name : Serine/threonine-protein kinase PAK 2
Alias : PAK2; Serine/threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58
Background:
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],


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