Signaling pathway

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CD166 (PN0301) Nb-FC recombinant antibody

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Article Number: PA0235
Delivery time: 现货
Price: 100ug/2200
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Target: CD131
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0307

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD131 protein.
Gene name : CSF2RB IL3RB IL5RB
Protein Name : CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
Alias : ALCAM;MEMD;CD166 antigen;Activated leukocyte cell adhesion molecule;CD166

Database connection:

Organism

Gene ID

SwissProt

Background:

CD131, also known as the IL-3R common β subunit , is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. The 1C1 antibody is a non-blocking antibody.

Cell localization : Membrane; Single-pass type I membrane protein.

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