Signaling pathway

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UNC5B Polyclonal Antibody

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Article Number: PG7767
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: UNC5B
Application: WB, ELISA
Reactivity : Human, Rat, Mouse
MW(Observed) : 103 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : UNC5B Polyclonal Antibody detects endogenous levels of protein.
Gene name : UNC5B P53RDL1 UNC5H2 UNQ1883/PRO4326
Protein Name : Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],

Cell localization : Cell membrane; Single-pass type I membrane protein. Membrane raft. Associated with lipid rafts.

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