Signaling pathway

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PDE10A Polyclonal Antibody

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Article Number: PD4140
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: PDE10A
Application: WB, ELISA, IHC
Reactivity : Human, Rat
MW(Observed) : 75 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : PDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.
Gene name : PDE10A
Protein Name : cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Alias : PDE10A; cAMP and cAMP-inhibited cGMP 3';5'-cyclic phosphodiesterase 10A

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],

Cell localization : Cytoplasm, cytosol .

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