Signaling pathway

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XDH Polyclonal Antibody

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Article Number: PG7184
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: XDH
Application: WB, ELISA
Reactivity : Human, Rat, Mouse
MW(Observed) : 146 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : XDH Polyclonal Antibody detects endogenous levels of protein.
Gene name : XDH XDHA
Protein Name : Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (Xanthine oxidoreductase) (XOR)]

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014],

Cell localization : Cytoplasm . Peroxisome . Secreted.

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