Signaling pathway

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C11B2 Polyclonal Antibody

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Article Number: PG6991
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: C11B2
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 55 kD
Host Species: Rabbit
Isotype : IgG

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Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : C11B2 Polyclonal Antibody detects endogenous levels of protein.
Gene name : CYP11B2
Protein Name : Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

cytochrome P450 family 11 subfamily B member 2(CYP11B2) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008],

Cell localization : Mitochondrion inner membrane ; Peripheral membrane protein .

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