Signaling pathway

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UGT1A9 rabbit pAb

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Article Number: PG5718
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560

Detailed Information

Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of UGT1A9 at Human/Mouse
Gene name : UGT1A9 GNT1 UGT1
Protein Name : UGT1A9
Alias : UDP-glucuronosyltransferase 1-9; UDPGT 1-9; UGT1*9; UGT1-09; UGT1.9; UDP-glucuronosyltransferase 1-I; UGT-1I; UGT1I; UDP-glucuronosyltransferase 1A9; lugP4;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008],

Cell localization : Endoplasmic reticulum membrane ; Single-pass membrane protein .

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