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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH1319
Delivery time: 一周
Price: 100 μL/2200
Category:
Target： uMtCK
Application： World Bank
Reactivity ： Human,Mouse,Rat,Dog,Pig,Rabbit
MW(CalcμLated) ： 47 kD
Host Species： Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： WB 1:1000-1:2000;Not yet tested in other applications.
Compose ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process ： Affinity purification
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Antigen & Target Information
Specificity ： uMtCK Monoclonal Antibody detects endogenous levels of uMtCK protein.
Gene name ： CKMT1A/CKMT1B
Protein Name ： Creatine kinase U-type mitochondrial
Alias ： CKMT1A;CKMT;CKMT1B;CKMT;Creatine kinase U-type;mitochondrial;Acidic-type mitochondrial creatine kinase;Mia-CK;Ubiquitous mitochondrial creatine kinase;U-MtCK
Database connection:
Background：
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mi
Cell localization ： Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
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Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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