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Signaling pathway
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Neurodegeneration—A Common Pathway Across Multiple Diseases (0)
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The AGE–RAGE signaling pathway in diabetic complications (0)
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PD-L1 Expression and the PD-1 Checkpoint Pathway in Cancer (0)
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Glioma-associated Kaposi’s sarcoma-associated herpesvirus infection (0)
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH0604
Delivery time: 一个月
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： Glutamine synthetase
Application： WB, IF, ELISA, IHC
Reactivity ： Human,Mouse,Rat,
MW(CalcμLated) ： 42 kDa
MW(Observed) ： 42 kDa
Host Species： Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： PTR1400
Antigen & Target Information
Specificity ： This antibody detects endogenous levels of Gl Syn/Glutamine Synthetase protein.
Gene name ： GLUL
Protein Name ： Glutamine synthetase
Alias ： GLUL;GLNS;Glutamine synthetase;GS;Glutamate decarboxylase;Glutamate--ammonia ligase
Database connection:
Background：
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
Cell localization ： Membrane, Cytoplasm
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Centered on our primary and secondary antibody products, we have established a strong foothold in the specialized antibody reagent market. Leveraging our independently developed core technology platform and a dedicated R&D and manufacturing team, we provide high‑reliability biological reagents and end‑to‑end technical solutions to universities, research institutes, biopharmaceutical companies, and other customers worldwide.
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Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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